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TWIST1 regulation of circRNA: a novel mechanism to promote epithelial-mesenchymal transition in hepatocellular carcinoma

   
@article{NCRI4871,
	author = {Zachary A. Yochum and Timothy F. Burns},
	title = {TWIST1 regulation of circRNA: a novel mechanism to promote epithelial-mesenchymal transition in hepatocellular carcinoma},
	journal = {Non-coding RNA Investigation},
	volume = {2},
	number = {0},
	year = {2018},
	keywords = {},
	abstract = {The epithelial-mesenchymal transition (EMT) is a process in which epithelial cells reversibly transdifferentiate and adopt a mesenchymal morphology (1-3). EMT is driven by suppression of epithelial associated genes such as E-cadherin and upregulation of mesenchymal associated genes such as fibroblast-specific protein 1 and Vimentin (1-3). These genetic changes lead epithelial cells to become more spindle-like in appearance due to loss of epithelial cell apical-basal polarity, cell-cell interactions, and cell-extracellular matrix interactions (1).},
	issn = {2522-6673},	url = {https://ncri.amegroups.org/article/view/4871}
}