Review Article
Non-coding RNA in relation to autism spectrum disorder
Abstract
Autism spectrum disorder (ASD) is a neurodevelopmental disorder that represents a serious public health concern due to its increasing prevalence rates, severity of symptoms, and absence of a causal treatment. Increasing number of experimental studies as well as review articles indicate that dysregulation of non-coding RNAs (ncRNAs) contribute to ASD development. Some ncRNA have been already suggested as biomarkers for ASD screening. This review highlights the importance of all types of ncRNA already investigated in relation to ASD. Additionally, the most frequent study limitations are discussed at the end of this paper.